EMSS Research Grant Awardees

EMSS Member:   A/Prof Melvin Leow Khee Shing

Research Title:  Elucidation of the molecular structure of the catalytic domain of human thyroid peroxidase

Year Research Grant Awarded:  July 2017

Amount:  SGD30,000 over 3 years


EMSS Member:   Dr Lim Wei Ying

Research Title:  Real-time CGM in women with gestational diabetes mellitus

Year Research Grant Awarded:  July 2017

Amount:  SGD30,000 over 3 years


EMSS Member:   Dr Rajeev Parameswaran

Research Title:  Prospective pilot study of tumour associated glycan expression in patients with indeterminate (Bethesda II) thyroid nodules – a multicenter study

Year Research Grant Awarded:  July 2017

Amount:  SGD30,000 over 3 years


EMSS Member:   Dr Khoo Chin Meng

Research Title:  Effect of single meal to high fat, high protein or high carbohydrate diet on secretion of gastrointestinal hormones in obese insulin resistance vs lean insulin sensitive healthy subjects

Year Research Grant Awarded:  Jan 2015

Amount:  SGD30,000 over 3 years


EMSS Member:   Dr Rinkoo Dalan

Research Title:  Genetic Risk Score Associations with cardiovascular disease in Indian Type 2 Diabetes Mellitus (T2DM) patients: A case-control pilot study

Year Research Grant Awarded:  Jan 2015

Amount:  SGD30,000 over 3 years


EMSS Member:   Dr Lim Su Ping Brenda

Research Title:  Identifying clinical features and optimal treatment of “rapid-responder” Graves’ thyrotoxicosis: a prospective nested case-control study

Year Research Grant Awarded:  Jan 2015

Amount:  SGD30,000 over 3 years


EMSS Member:   Dr Yang Peiling Samantha

Research Title:  The clinical validation of Thyroseq v2 Next Generation Sequencing Assay for the prediction of thyroid malignancy in thyroid nodules with indeterminate cytology in the Asian population

Year Research Grant Awarded:  Jan 2015

Amount:  SGD30,000 over 3 years

Papers published from this project:

  1. Performance of a Multigene Genomic Classifier in Thyroid Nodules With Indeterminate Cytology A Prospective Blinded Multicenter Study

David L. Steward, MD; Sally E. Carty, MD; Rebecca S. Sippel, MD; Samantha Peiling Yang, MBBS, MRCP, MMed; Julie A. Sosa, MD, MA; Jennifer A. Sipos, MD; James J. Figge, MD, MBA; Susan Mandel, MD, MPH;Bryan R. Haugen, MD; Kenneth D. Burman, MD; Zubair W. Baloch, MD, PhD; Ricardo V. Lloyd, MD, PhD;Raja R. Seethala, MD; William E. Gooding, MS; Simion I. Chiosea, MD; Cristiane Gomes-Lima, MD; Robert L. Ferris, MD, PhD; Jessica M. Folek, MD; Raheela A. Khawaja, MD; Priya Kundra, MD;Kwok Seng Loh, MBBS; Carrie B. Marshall, MD; Sarah Mayson, MD; Kelly L. McCoy, MD; Min En Nga, MBBS;Kee Yuan Ngiam, MBBS, MRCS, MMed; Marina N. Nikiforova, MD; Jennifer L. Poehls, MD; Matthew D. Ringel, MD; Huaitao Yang, Md, PhD; Linwah Yip, MD; Yuri E. Nikiforov, MD, PhD


EMSS Member:   A/Prof Melvin Leow Khee Shing

Research Title:  Exploring the Role of epigenetic mechanisms in the tempora regulation of TSH gene expression in thyrotoxicosis and hypothyroidism

Year Research Grant Awarded:  Dec 2010

Amount:  SGD20,000 over 3 years

Papers published from this project:

  1. Ohba K, Leow MK, Singh BK, Sinha RA, Lesmana R, Liao XH, Ghosh S, Refetoff S, Sng JC, Yen PM. Desensitization and incomplete recovery of hepatic target genes after chronic thyroid hormone treatment and withdrawal in male adult mice.Endocrinology 2016; 157: 1660-72. (IF = 4.286)”
  2. Ohba K, Sinha R, Singh B, Zhou J, Kovalik JP, Liao XH, Refetoff S, Sng J, Leow MK, Yen PM. Changes in hepatic TRb protein expression, lipogenic gene expression, and long chain acylcarnitine levels during chronic hyperthyroidism and T3 withdrawal in a mouse model. Thyroid 2017; 27(6):852-860. doi: 10.1089/thy.2016.0456. (IF=3.544)”

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